Production of gamma-aminobutyric acid by lactic acid bacteria of marine origin from Vietnam

Gamma-aminobutyric acid (GABA) is a non-proteinogenic amino acid, which functions as neurotransmitter in the central nervous system. GABA has been shown to have several positive effects on human health, including reducing anxiety and promoting relaxation. In this study, various fermented fish products were screened for their ability produce GABA. A total of 35 lactic producing strains isolated from 8 samples marine organism, 10 found GABA-producing abilities. These identified using 16S rDNA sequencing. The concentrations produced by isolates ranged 725 5590 mg/L. Lactobacillus brevis GB111 best strain, with conversion rate up 90.3%, suggests that these may potential applications food pharmaceutical industries source